Swansea University Medical School
Deya’s research focuses on gene expression and function in the uterus and its relationship to fertility and cancer. Her clinical interests are Polycystic Ovary Syndrome (PCOS), endometriosis, unexplained infertility and gynaecological cancers (endometrial, ovarian and cervical cancer). She has strategic collaborations with clinicians at Abertawe Bro Morgannwg University NHS health board, developing cellular and molecular approaches to determine mechanisms underlying gynaecological pathologies, to identify biomarkers. Her projects on endometrial implantation and differentiation, relate to L-selectin ligands (MUC1), hormone nuclear receptors and WT1 pathway. Her research in gynaecological cancer includes the regulation of tamoxifen target genes in endometrium and new methods to identify biomarkers for pre-disposition of infertile women to develop gynaecological cancers. She leads an international research network (Prof. Rojas, Catholic University of Maule and Dr. Gracia, Director of Maule Clinic, Chile), studying protein glycation in relation to altered endometrial function. Her aim is to translate basic research into clinically relevant observations for patient benefit. Her projects involve collaboration with the private sector to expedite validation of clinical diagnostic biomarkers and the development of new drug leads for targeted cancer therapy. She also has multidisciplinary collaborations in the area of nanosensors and improved performance medications in the field of human reproductive biology and hormone therapy. She has received research grant valuing over £1m in the recent years. Deya has published more than 20 articles during her career on human, animal, plant and yeast research. She is a member of the Endocrine Society and acts as an expert reviewer for Journal of Clinical Endocrinology and Metabolism, Human Reproduction and others. She teaches within the Genetics & Biochemistry (College of Medicine) and Biomedical Engineering (College of Engineering) undergraduate programmes.