Endocrinology, Diabetes and Metabolism

Pituitary Adenomas

Pituitary adenomas (PA) are a common type of endocrine neoplasia that is usually benign. PA have a high rate of clinical morbidity due to hormonal hypersecretion, neurological symptoms from cerebral mass effects or invasion of adjacent structures, and secondary hypopituitarism. Pharmacological treatment, primarily dopamine agonists (DA) and somatostatin analogues (SSA), surgery, and radiotherapy are being used to treat them [2]. Despite substantial progress in the treatment of PA, a significant portion of individuals remain uncontrollably ill. Long-term uncontrolled pituitary hormone hypersecretion, which can lead to serious systemic illnesses as well as tumour recurrence or aggressiveness, is still a difficult clinical problem.