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7th European Diabetes and Endocrinology Congress, will be organized around the theme “New Approaches for Diabetes and Endocrinology”

Euro Endocrinology 2018 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Euro Endocrinology 2018

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Endocrinology is a complex study of the various hormones and their actions and disorders in the body. Glands are organs that make hormones. These are substances that help to control activities in the body and have several effects on the metabolism, reproduction, food absorption and utilization, growth and development etc. Hormones also control the way an organism responds to their surroundings and help by providing adequate energy for various functions. Diabetes is caused by reduced production of insulin, or by decreased ability to use insulin. Insulin, the hormone produced by the beta cells in the pancreas, allows blood sugar (glucose) cells to be able to use blood sugar. This hormone is necessary for glucose to go from the blood to the inside of the body cells. With inadequate insulin, glucose builds up in the bloodstream instead of going into the cells. The body is unable to use glucose for energy despite the high levels of glucose in the bloodstream. This causes the excessive thirst, urination, and hunger, which are the most common symptoms of diabetes. The excess sugar remains in the blood and is then removed by the kidneys. This disease occurs in several forms, but the most common are Type I Diabetes or Juvenile Onset Diabetes or Insulin-Dependent Diabetes Mellitus (IDDM), Type II or Non-Insulin Dependent Diabetes Mellitus (NIDDM), and Gestational.

  • Track 1-1Congenital adrenal hyperplasia (CAH)
  • Track 1-2Graves’ disease
  • Track 1-3Hypoglycaemia
  • Track 1-4Hyperthyroidism
  • Track 1-5Hypothyroidism
  • Track 1-6 Osteoporosis
  • Track 1-7Polycystic ovary syndrome (PCOS)
  • Track 1-8Gestational Diabetes (Diabetes During Pregnancy)
  • Track 1-9Prediabetes
  • Track 1-10Type 1 Diabetes
  • Track 1-11Type 2 Diabetes

The endocrine system controls the flow of information between cells and tissues, governed by complex regulatory mechanisms. Hormones exert widespread influences on various metabolic processes which ensure regulatory, morph genic and integrative function. Signs and symptoms of endocrine disorders span the entire clinical spectrum. Manifestations of endocrine diseases are frequently due to non‐endocrine or unknown causes such as fatigue, malaise, weakness, headache, anorexia, depression, weight gain or loss. Endocrine diseases are therefore, easily recognisable in their extreme forms and arriving at clear diagnosis can sometimes be difficult.  Early diagnosis and management of endocrine diseases are essential and can be achieved by the combination of targeted endocrine testing, imaging, careful history, physical examination and sound clinical judgement. Adequate knowledge and understanding of basic science and principles of endocrinology are important tools for the enhancement of efficiency and accuracy‐goals of endocrine function testing. The perfect strategy for targeted endocrine investigation would achieve the ideals of reaching specific diagnosis in the shortest time, with minimum inconvenience and cost on the patient.

  • Track 2-1Vitamin D deficiency and management guidelines
  • Track 2-2Osteoporosis- Causes and treatment
  • Track 2-3Novel insights into management of growth hormone deficiency
  • Track 2-4cardiovascular conventional and non-conventional risk factors
  • Track 2-5New aspects of rickets management

Pediatric endocrinology is a medical subspecialty dealing with disorders of the endocrine glands, such as variations of physical growth and sexual development in childhood, diabetes and many more. By age, pediatric endocrinologists, depending upon the age range of the patients they treat, care for patients from infancy to late adolescence and young adulthood. By disease, the most common disease of the specialty is type 1 diabetes, which usually accounts for at least 50% of a typical clinical practice. The next most common problem is growth disorders, especially those amenable to growth hormone treatment. Pediatric endocrinologists are usually the primary physicians involved in the medical care of infants and children with intersex disorders. The specialty also deals with hypoglycaemia and other forms of hyperglycemia in childhood, variations of puberty, as well other adrenal, thyroid, and pituitary problems. Many pediatric endocrinologists have interests and expertise in bone metabolism, lipid metabolism, adolescent gynecology, or inborn errors of metabolism.

  • Track 3-1Immune influences on behavior and endocrine activity in early-experience and maternal separation paradigms
  • Track 3-2Androgens, cognition, and social behavior in children
  • Track 3-3Integrating Child Developmental Research & endocrinology
  • Track 3-4Pituitary & Pediatric endocrinology
  • Track 3-5MicroRNAs as a potential tool in the diagnosis of endocrine disease
  • Track 3-6Enlarged thyroid gland (goiter)
  • Track 3-7Underactive or overactive thyroid gland
  • Track 3-8Pituitary gland hypo/hyper function
  • Track 3-9Adrenal gland hypo/hyper function
  • Track 3-10Ambiguous genitals/intersex
  • Track 3-11Ovarian and testicular dysfunction
  • Track 3-12Diabetes
  • Track 3-13Low blood sugar (hypoglycemia)
  • Track 3-14Obesity
  • Track 3-15Problems with Vitamin D (rickets, hypocalcemia)

Neuroendocrinology is the study of the interaction between the nervous system and the endocrine system, including the biological features of the cells involved, and how they communicate. The nervous and endocrine systems often act together in a process called neuroendocrine integration, to regulate the physiological processes of the human body. Neuroendocrinology arose from the recognition that the brain, especially the hypothalamus, controls secretion of pituitary gland hormones, and has subsequently expanded to investigate numerous interconnections of the endocrine and nervous systems. The neuroendocrine system is the mechanism by which the hypothalamus maintains homeostasis, regulating reproduction, metabolism, eating and drinking behaviour, energy utilization, osmolality and blood pressure.

  • Track 4-1Psych neuroendocrinology of functional somatic disorders
  • Track 4-2Advancements in neuroendocrinology
  • Track 4-3The endocrine study of depression
  • Track 4-4Molecular Hormone Action
  • Track 4-5Steroids and the Nervous System
  • Track 4-6Estrogen, Stress, and Depression: A Neurocognitive Model
  • Track 4-7Perimenopausal depression
  • Track 4-8Antidepressants associated hyponatremia & Endocrinologist Role
  • Track 4-9Endocrinology & Recurrent Depressive Disorder
  • Track 4-10Molecular neuroscience
  • Track 4-11 Neurochemistry
  • Track 4-12 Neuroendocrine
  • Track 4-13Neuropharmacology
  • Track 4-14Neurobiological brain disorder

Thyroid problems are not rare in children, but they are not as common as parents. Hyperthyroidism an overactive thyroid gland, is seen only occasionally in new-borns. This condition is referred to as neonatal hyperthyroidism. Although thyroid disease occurs less frequently in children than in adults, the signs and symptoms can be similar. However, there are a few important differences that need to be brought to light. Congenital hypothyroidism is a disorder that affects infants at birth, and occurs in about 1 in 4000 live-born babies. It is characterised by the loss of thyroid function, due to the thyroid gland failing to develop normally. In some cases, the gland is totally absent. About 10 per cent of cases are caused by an enzyme defect leading to deficient hormones production, iodine deficiency and a brain pituitary gland abnormality. If the diagnosis is delayed, and immediate treatment is not given, congenital hypothyroidism can lead to growth and developmental defects, and severe mental retardation (cretinism).

  • Track 5-1Hypothyroidism in New born
  • Track 5-2Effect of Thyroidism on Unborn baby & Neonates
  • Track 5-3Pediatric Hypernatremia, Raynaud Phenomenon, Acute Anemia
  • Track 5-4Hashimoto’s & Postpartum Thyroiditis
  • Track 5-5Management of Hyper & Hypothyroidism during Pregnancy
  • Track 5-6Infertility, Miscarriage & Complications during Pregnancy & Childbirth
  • Track 5-7Clinical and Diagnosis Features

Treat patients with hyperparathyroidism, Address specific issues of Graves' disease including thyrocardiac disease,  ophthalmopathy, dermopathy, prolonged pregnancy, mammary, Use the 2015 ATA guidelines in the management of their patients with thyroid nodules and thyroid cancer diagnosis, Determine when to do molecular genetic testing during evaluation of a thyroid nodule, Identify the commonly encountered adrenal and pituitary disorders (clinical cases), Counsel patients on fertility issues when being treated for cancer, Provide the best treatment for transgender patients, Use the new lipid lowering agents and how to manage patient who cannot take statins. Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroid genesis).

  • Track 6-1Islet cell transplantation
  • Track 6-2Case management in multiple pituitary hormone deficiencies
  • Track 6-3Updated approach for the management of thyroid nodules
  • Track 6-4Endocrine disorders in hemoglobinopathies
  • Track 6-5Adrenal hyperplasia
  • Track 6-6Lipid metabolism by glucocorticoids

Endocrine glands, they are the hormone-producing glands in the body, and the common ones are thyroid, parathyroid hormones, pancreas and adrenal glands. If the thyroid endocrinology is making extra prohormones, a patient will have symptoms like anxiety, tremors, sweating, palpitations, or difficulty falling asleep. Initially, this is managed with medication, or there are pills like radioactive iodine that can destroy the thyroid gland. Endocrine disruptors are chemicals that, at certain doses, can interfere with the endocrine (or hormone) system in mammals. These disruptions can cause cancerous brain tumors, birth defects, and other developmental disorders. Addison's disease (also Addison disease, chronic adrenal insufficiency, hypocortisolism, and hypoadrenalism) is a rare, chronic endocrine system disorder in which the adrenal glands do not produce sufficient steroid hormones (glucocorticoids and mineralocorticoids).

  • Track 7-1Gitelman syndrome
  • Track 7-2Molecular Endocrinology of Breast Cancer
  • Track 7-3Pheochromocytoma- Diagnosis and treatment
  • Track 7-4Addison’s disease
  • Track 7-5Metabolic Syndrome- Diagnosis and treatment
  • Track 7-6Endocrine disruptors
  • Track 7-7Cushing’s syndrome
  • Track 7-8Sheehan’s syndrome

Novel therapeutic targets available for diabetes includes Incretion based therapies, oral therapeutic agents like secretagogues, beta cell regeneration & proliferation and stem cell therapies. Embryonic stem cell and fetal precursor cell transplantation therapies are the major stem cell therapies available for Diabetes. Apart from the above, various computational approaches in Diabetes management control have been introduced recently which are playing an important role in identification of genes causing diabetes helping in Early Detection of Diabetes. These processes are also useful in studying the chemical etiologies of Diabetes uncovering various treatment prospects and model construction processes for survival prediction.

  • Track 8-1Non-invasive diagnostic tool for detecting cardiovascular disease in diabetes
  • Track 8-2Diabetes and cancer
  • Track 8-3Oral therapies: secretagogues
  • Track 8-4Incretin based therapies
  • Track 8-5Novel agents in treatment
  • Track 8-6Updates of anti-diabetic agents
  • Track 8-7Measurement of insulin resistance and secretion in diabetes clinic
  • Track 8-8Diabetes Case Reports

Diabetes mellitus type 1 (also known as type 1 diabetes) is a form of diabetes mellitus that results from the autoimmune destruction of the insulin-producing beta cells in the pancreas. The subsequent lack of insulin leads to increased glucose in the blood and urine. The classical symptoms are frequent urination, increased thirst, increased hunger, and weight loss. The cause of diabetes mellitus type 1 is unknown. Type 1 diabetes can be distinguished from type 2 by autoantibody testing. The C-peptide assay, which measures endogenous insulin production, can also be used.

Administration of insulin is essential for survival. Insulin therapy must be continued indefinitely and typically does not impair normal daily activities. People are usually trained to independently manage their diabetes; however, for some this can be challenging. Untreated, diabetes can cause many complications. Acute complications include diabetic ketoacidosis and nonketotic hyperosmolar coma. Serious long-term complications related to high blood sugar include heart disease, stroke, kidney failure, foot ulcers and damage to the eyes. Furthermore, complications may arise from low blood sugar caused by excessive insulin treatment.

Diabetes mellitus type 1 accounts for between 5% and 10% of all diabetes cases. Globally, the number of people with DM type 1 is unknown,  although it is estimated that about 80,000 children develop the disease each year. Within the United States the number of affected persons is estimated at one to three million. The development of new cases varies by country and region: the lowest rates appear to be in Japan and China, with approximately 1 person per 100,000 per year; the highest rates are found in Scandinavia, where rates are closer to 35 new cases per 100,000 per year. The United States and other countries in northern Europe fall somewhere in between, with 8-17 new cases per 100,000 per year.

  • Track 9-1A1C test
  • Track 9-2Blood pressure test
  • Track 9-3Pancreas transplant animation
  • Track 9-4 Fatigue
  • Track 9-5Frequent urination
  • Track 9-6Sisters’ Bone Marrow Transplant
  • Track 9-7Stem cell transplant
  • Track 9-8Urinalysis
  • Track 9-9Polyuria
  • Track 9-10Polydipsia
  • Track 9-11Polyphagia

Diabetes mellitus type 2 is a long term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Symptoms may also include increased hunger, feeling tired, and sores that do not heal. Often symptoms come on slowly. Long-term complications from high blood sugar include heart disease, strokes, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to amputations. The sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon. Type 2 diabetes is partly preventable by staying a normal weight, exercising regularly, and eating properly. Treatment involves exercise and dietary changes. If blood sugar levels are not adequately lowered, the medication metformin is typically recommended. Many people may eventually also require insulin injections. In that on insulin, routinely check blood sugar levels is advised, however this may not be needed in those taking pills. Bariatric surgery often improves diabetes in those who are obese.

Rates of type 2 diabetes have increased markedly since 1960 in parallel with obesity. As of 2013 there were approximately 368 million people diagnosed with the disease compared to around 30 million in 1985. Typically it begins in middle or older age,although rates of type 2 diabetes are increasing in young people. Type 2 diabetes is associated with a ten-year-shorter life expectancy. Diabetes was one of the first diseases described. The importance of insulin in the disease was determined in the 1920s.

  • Track 10-1Frequent urination
  • Track 10-2Glucose tolerance test
  • Track 10-3Unexplained weight loss
  • Track 10-4Heart and blood vessel disease
  • Track 10-5Nerve damage (neuropathy)
  • Track 10-6Kidney damage (nephropathy)
  • Track 10-7Hearing impairment

Diabetes, often referred to by doctors as diabetes mellitus, describes a group of diabetes and metabolic diseases in which the person has high blood glucose (blood sugar), either because insulin production is inadequate, or because the body's cells do not respond properly to insulin, or both. Patients with high blood sugar will typically experience polyuria (frequent urination), they will become increasingly thirsty (polydipsia) and hungry (polyphagia). Distinguishing between type 1 and type 2 diabetes at diagnosis is important. Typical characteristics of type 2 diabetes include the, Slow and insidious onset, Most common in overweight or obese patients from a minority group (Native Americans, blacks, and Pacific Islanders), Signs of insulin resistance, Strong family history of type 2 diabetes: Familial lifestyle risk factors leading to obesity may be present, as may a family history of cardiovascular disease or metabolic syndrome. Pediatric Diabetes is a type 1 diabetes mellitus requires insulin therapy.

  • Track 11-1Type 1 & 2 diabetes Complications and treatment
  • Track 11-2Paediatric diabetes and treatment
  • Track 11-3Gestational Diabetes- Treatment and care
  • Track 11-4Dietary management, physical activity and prevention strategies
  • Track 11-5Novel research and treatment strategies on diabetes

The concept of 'new technologies' for type 1 diabetes and new discovery and advanced type 2 diabetes treatment has expanded in recent years at a rate that some might consider comparable to 'Moore’s Law', and the sheer number of new technologies entering into the type 1 diabetes marketplace is also growing at a remarkable rate. From the patient’s perspective, this is not only exciting but can lead to a sense of optimism. Technologies that today are growing commonplace (e.g. insulin pumps, rapid HbA1c monitoring, etc come under new therapeutic mechanisms of diabetes. Indeed, it could be argued that the major advances in type 1 diabetes care made within the last quarter of a century have come from technology rather than biology. At the same time, not all new technologies succeed (e.g. the Glucowatch), regardless of their purported promise. Bothtype 1 diabetes patients and their healthcare providers will soon see a series of further advanced medical technologies used in hospital and new technologies and novel therapies in diabetes treatment whose basis is tied to the notion of improving the lives of those with the disease.

  • Track 12-1New Discoveries and Emerging Therapies for Type 1 Diabetes
  • Track 12-2New Discovery and Treatment for Type 2 Diabetes
  • Track 12-3New Therapeutic Mechanisms for Diabetes
  • Track 12-4Other advanced medical technologies used in hospitals
  • Track 12-5Exploring novel therapies in diabetes treatment

Track-13: Case Reports and Others

Lipid disorders are a group of medical conditions which refer to excessive levels of fatty substances in the bloodstream. These fatty substances include cholesterol and triglycerides. An excess of bad cholesterol increases your risk of heart disease and stroke. A paraganglioma is rare neuroendocrine neoplasm that may develop at various body sites (including the head, neck, thorax and abdomen). About 97% are benign and cured by surgical removal; the remaining 3% are malignant neoplasm because they are able to produce distant metastases. "Paraganglioma" is now the most-widely accepted term for these lesions that have been also described as: glomus tumour, chemodectoma, perithelioma, fibroangioma, and congenital nevi.Metabolic disorders of bone strength, usually caused by abnormalities of minerals (such