Diabetic Ketoacidosis (DKA)

Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Diabetic ketoacidosis arises because of a lack of insulin in the body. The lack of insulin and corresponding elevation of glucagon leads to increased release of glucose by the liver (a process that is normally suppressed by insulin) from glycogen via glycogenolysis and also through gluconeogenesis. Diabetic ketoacidosis occurs in 4.6–8.0 per 1000 people with diabetes annually.

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